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Introduction: A complete blood count (CBC), also known as a complete blood cell count, full blood count (FBC), or full blood exam (FBE). CBC is a blood panel that gives information about the cells that circulate in the bloodstream – white blood cells (leukocytes) – red blood cells (erythrocytes) and – platelets (thrombocytes)   Importance: CBC is done to monitor overall health, to screen for some diseases, to confirm a diagnosis of some medical conditions, to monitor a medical condition, and to monitor changes in the body caused by medical treatments.  This common blood test measures the amount of various types of blood cells in a sample of your blood. Blood cancers may be detected using this test if too many or too few of a type of blood cell or abnormal cells are found. A bone marrow biopsy may help confirm a diagnosis of a blood cancer.  Abnormally high or low counts may indicate the presence of many forms of disease, and hence blood counts are amongst the mo

Here one of Example of Infertility Panel like AMH Plus TESTS IN THIS PANEL : AMH, LH, FSH, PROLECTIN, ESTRADIOL, TESTOSTRONE(FREE & TOTAL), TSH 3G Purpose : To Discover Manage and Track Fertility with Non-invasive method Need:  Ovulatory Dysfunction is identified in approx. 15% of all infertile coup;es and accounts for upto 40% of infertility in women according to Diagnostic evaluation of the Infertile Female: a Committee Opinion; Fertility sterility Vol 103, (6) June 2015 Cause of Ovulatory Disfuntion:  Most common cause of Ovulatory dysfunction are PCOS, Thyroid disorders and Hyperprolectinemia Features:  Provides comprefhensive evaluation of "Ovulatory dysfunction"  Helps to assess the overian reserve of patient  Lower AMH Levels(less than 1 ng/ml) indicate: a) Poor response to ovarian stimulation, b)Poor pregnancy outcomes in IVF  High levels of AMH indicate PCOS  One Step Diagnostic Solution for Female Infertility Benefits of this Panel

Nematode Introduction: Filariasis is, a disease group affecting humans, caused by nematode parasites of the order Filariidae, and transmitted by mosquitoes - Culex quinquefasciatus is globally the most important vector. 3 of the species are primarily responsible for most cases of human Filariasis • Wucheraria bancrofti (lymphatic) • Brugia malayi (lymphatic) • Onchocerca volvulus (subcutaneous) Loa Lo Parasite India is one of the five countries with the highest estimated disease burden worldwide (~38%). 115 million cases worldwide (45.5 million India, 40 million subsaharan Africa).  Sign and Symp toms: Filiriasis Patient  The most spectacular symptom of lymphatic filariasis is elephantiasis—edema with thickening of the pores and skin and underlying tissues—which become the primary disorder discovered to be transmitted with the aid of mosquito bites. Elephantiasis effects when the parasites lodges in the lymphatic systems.   Diagnosis of Fi

What is PCR? Polymerase Chain Reaction (PCR) PCR is a laboratory method used for making a very large number of copies of short sections of DNA from a very small sample of genetic material. This process is called "amplifying" the DNA and it enables specific genes of interest to be detected or measured. What is Real Time PCR? Real-time PCR can detect the amplification of products, as the products are synthesized. The real-time PCR uses a florescent dye system and thermocycler equipped with fluorescent- detection capability.  What is Diffrence Between Conventional PCR and Real Time PCR? Conventional PCR is more time consuming as it uses gel electrophoresis to analyze the amplified PCR products Where Real-time PCR uses fluorescent dye system and less time consuming as it can detect early phases of the reaction. Real-time PCR is more sensitive than conventional PCR Conventional PCR has very poor resolution while real-time PCR can detect very little ch

Introduction: About one in 800 babies is born with Down syndrome, caused by an extra copy of chromosome 21 (trisomy 21). The maternal Markers tests are blood tests available to pregnant women to help determine the risk of Down syndrome (trisomy 21), Edward syndrome (trisomy 18) or neural tube defects in their unborn child. These test are used to classify a patient as either high-risk or low-risk for chromosomal abnormalities (and neural tube defects). 1.     DOUBLE MARKER:   This is first trimester risk assessment . 2.     TRIPLE MARKER: This is 2 nd trimester risk assessment. 3.     Quadruple marker:   This is also 2 nd trimester risk assessment. Want to Buy Something Interesting? Advantage of Quadruple marker: ·         Enhanced accuracy with Prisca 5 Software using MoM(Multiple of Medians) of Indian data base ·         2. DIA levels are 2 fold higher in Down syndrome pregnancies ·         Easy to Perform rapid diagnosis, cost effective, no risk to f

This is screen shot of Directory of Services which shows test regarding Spinal Muscular Atrophy. Performing Location Mumbai And this is response we get through mail from SRL Customer Care

Introduction:  A blood culture is a test that looks for microorganisms in the blood. A doctor might order this test when a child has symptoms of an infection. Purpose of the Bactac Blood Culture:  To know the cause of Sepsis/Infection Disease condition with Sepsis:  Chills, fever, Nausea, Rapid breathing, rapid heartbeat Confusion, Less frequent urination What can be done about Sepsis? Saving lives depends not just on treatments specific to a particular infection, but rather a focus on early Recognition/Diagnosis and Awareness of sepsis  Features of Bactac Blood Culture over Conventional Methods: Antibiotic neutralizing resin media, thereby Bactac Blood Culture reduces false positivity by 1.5% and false negativity by 0.3% Can be performed even when patient is on antibiotic therapy Offers improved sepsis detection rate by 34% Specially useful for isolation of fastidious microorganisms, such as Brucella and S pneumoniae, especially from cerebrospinal and

What is AMH? AMH or Anti Mullerian Hormone is a substances produced by granulosa cells.  A granulosa cell or follicular cell is a somatic cell in ovary of female. Anti- Mullerian Hormone  or AMH is a protein that in humans is encoded by the AMH gene. It is a hormone that inhibits the development of the Müllerian ducts (paramesonephric ducts) in the male embryo. AMH level as Fertility Test? We assume AMH blood levels reflect the size of remaining eggs or ovarian reserve. And you know 1 in every 4 couples has been found to be affected by infertility as per WHO! Features of AMH as a Fertility Test? Earliest and most sensitive marker of Ovarian Reserve Non-cycle dependent- AMH can be measured on any day of the cycle Better Marker for Ovarian reserve- AMH is much more stable and better marker than FSH Earliest marker of Ovarian aging- AMH is earliest marker as AMH levels decline with age Result Interpretation of AMH Level for Adult Female under 35 Years:

Introduction : LPA(Line Probe Assay) or Hains test/ Molecular Methods is used to diagnose MDR/XDR TB Rapidly. This test is endorsed by WHO and FIND(Foundation for innovative new diagnostics. Line Probe Assay Steps :   DNA is extracted from M. tuberculosis isolates or directly from clinical specimens.  Polymerase chain reaction (PCR) amplification of the resistance-determining region of the gene under question is performed using biotinylated primers. Features of LPA or Hains Test : 1. Rapid genotypic test based on DNA strip technology 2. Rapid dterminationof genetic mutatins associated with spcific 1st line & 2nd line drugs. 3. Line Probe Assay (LPA) technology is suitable for use at national/central reference laboratories, or at laboratories where there is proven capacity to conduct molecular testing Resistance Vs Gene Mutation : Rifampicin : rPOB Isoniazid : KatG & inhA gene Fluroquinolones : gyra gene Aminoglycosides : rrs gene Cyclic pept